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Ann Thorac Surg 2010;89:981-983. doi:10.1016/j.athoracsur.2009.07.059
© 2010 The Society of Thoracic Surgeons
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Karthik Raghunathan
Rose Ganim
Gary Hochheiser
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Case Reports

Inhaled Epoprostenol During One-Lung Ventilation

Karthik Raghunathan, MD, MPHa,*, Neil Roy Connelly, MDa, Larry D. Robbins, DOa, Rose Ganim, MDb, Gary Hochheiser, MDb, Rebecca DiCampli, DOa

a Department of Anesthesiology, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts
b Division of Thoracic Surgery, Department of Surgery, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts

Accepted for publication July 10, 2009.

* Address correspondence to Dr Raghunathan, Department of Anesthesia, Tufts University School of Medicine, Baystate Medical Center, 759 Chestnut St, Springfield, MA 01199 (Email: karthik.raghunathan{at}bhs.org).

We used inhaled epoprostenol (with intravenous phenylephrine) during one-lung ventilation to improve oxygenation in a patient with severe interstitial lung disease undergoing video-assisted thoracoscopic surgery. The pharmacologic manipulation of pulmonary blood flow remains an underused strategy for the management of hypoxemia during one-lung ventilation.






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