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Ann Thorac Surg 2010;89:65-70. doi:10.1016/j.athoracsur.2009.10.026
© 2010 The Society of Thoracic Surgeons

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Kazuyoshi Tajima
Yoshiyuki Takami
Akihiko Usui
Yuichi Ueda
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Original Articles: Adult Cardiac

Early and Late Outcomes of Aortic Valve Replacement in Dialysis Patients

Keisuke Tanaka, MDa,*, Kazuyoshi Tajima, MDb, Yoshiyuki Takami, MDb, Noritaka Okada, MDb, Sachie Terazawa, MDa, Akihiko Usui, MD, PhDa, Yuichi Ueda, MD, PhDa

a Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
b Department of Cardiovascular Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan

Accepted for publication October 12, 2009.

* Address correspondence to Dr Tanaka, Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan (Email: ktanaka{at}med.nagoya-u.ac.jp).

Background: Few data are available on the outcomes of aortic valve replacement (AVR) in dialysis patients. Valve selection has been controversial, and systemic calcification in these patients has been an important concern. This study reports our experiences and evaluates whether dialysis patients can be treated in a way that is similar to nondialysis patients.

Methods: A retrospective review was performed on 73 AVRs (43 men, 29 women), including one redo operation, for dialysis patients between 1995 and 2007. Mean age was 65.0 ± 8.3 years. The bioprosthesis was basically selected for elderly patients as for nondialysis patients.

Results: For a severely calcified ascending aorta, the femoral or subclavian artery was selected for arterial cannulation in 9 patients (12.3%), and aortic cross-clamping under temporary circulatory arrest with moderate hypothermia was applied in 17 (23.3%). Implanted were 51 mechanical and 22 bioprosthetic valves. Four elderly patients in poor general condition received high-performance mechanical valves instead of bioprosthesis to avoid aortic root enlargement. There was no stroke during the perioperative period. Hospital mortality was 6.8%. The overall actuarial survival rate was 74.6% ± 5.6%, 55.7% ± 7.6%, and 39.9% ± 9.7% at 3, 5, and 10 years, respectively.

Conclusions: The results for the dialysis patients after AVR were satisfactory. Dialysis patients can be treated in AVR just like nondialysis patients. Valve selection and surgical strategy on a case-by-case basis are important to improve the clinical outcomes in dialysis patients.


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