HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): William M. DeCampli Monica C. Olsen Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by DeCampli, W. M. Articles by Felix, D. E. Search for Related Content PubMed PubMed Citation Articles by DeCampli, W. M. Articles by Felix, D. E. Related Collections Congenital - cyanotic Related Article

---

Original Articles: Pediatric Cardiac

Perioperative Hyperglycemia: Effect on Outcome After Infant Congenital Heart Surgery

^a Congenital Heart Institute, Arnold Palmer Hospital for Children, Orlando, Florida
^b University of Central Florida College of Medicine, Orlando, Florida

Accepted for publication August 25, 2009.

^_* Address correspondence to Dr DeCampli, Congenital Heart Institute, Arnold Palmer Hospital for Children, 50 W Sturtevant St, Orlando, FL 32806 (Email: william.decampli{at}orlandohealth.com).

Background: Studies demonstrate that cardiopulmonary bypass (CPB) causes intraoperative and postoperative hyperglycemia. Hyperglycemia has been associated with morbidity and mortality after infant cardiac surgery. We studied the effects on early postoperative outcomes of glucose (GLU) changes during and after pediatric cardiac surgery.

Methods: The records of 144 infants less than 10 kg who underwent CPB for a variety of congenital cardiac procedures were reviewed. The GLU values (at multiple intervals during and after surgery), age, weight, CPB time, ultrafiltration volume, and risk adjustment for congenital heart surgery (RACHS-1) score were recorded. Univariate and multivariate linear and binary logistic regression were used to examine the dependence of the composite outcome mortality or postoperative infection, the mechanical ventilation time (VENT time), and the length of stay (LOS), on these variables.

Results: The RACHS-1 score was the only significant predictor of the composite variable "mortality or infection" (p = 0.008). Glucose at any time was not a significant factor predicting this outcome. Lower pre-CPB GLU, younger age, and higher RACHS-1 score were significant predictors of greater LOS and VENT time.

Conclusions: In this study, post-CPB and postoperative hyperglycemia were not risk factors for postoperative morbidity and mortality after infant cardiac surgery.

Related Article

Invited Commentary

James Jaggers
Ann. Thorac. Surg. 2010 89: 185-186. [Extract] [Full Text] [PDF]

This article has been cited by other articles:

				S. M. Schwartz, K. J. S. Anand, M. A. Portman, S. Crow, D. P. Nelson, and J. J. Zimmerman Endocrinopathies in the Cardiac ICU World Journal for Pediatric and Congenital Heart Surgery, July 1, 2011; 2(3): 400 - 410. [Abstract] [Full Text] [PDF]

				J. Jaggers Invited Commentary Ann. Thorac. Surg., January 1, 2010; 89(1): 185 - 186. [Full Text] [PDF]