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Ann Thorac Surg 2009;88:2018-2019. doi:10.1016/j.athoracsur.2009.01.047
© 2009 The Society of Thoracic Surgeons

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Kausik Bhattacharya
Vipin Zamvar
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Case Reports

Platypnea-Orthodeoxia Syndrome: A Rare Complication After Right Pneumonectomy

Kausik Bhattacharya, FRCS, CTha,*, Rashmi Birla, MBBSa, David Northridge, FRCPb, Vipin Zamvar, FRCS, CTha

a Department of Cardiothoracic Surgery, Edinburgh Royal Infirmary, Edinburgh, United Kingdom
b Department of Cardiology, Edinburgh Royal Infirmary, Edinburgh, United Kingdom

Accepted for publication January 20, 2009.

* Address correspondence to Dr Bhattacharya, Department of Cardiothoracic Surgery, Edinburgh Royal Infirmary, Dalkeith Rd, Edinburgh, EH16 4SA, United Kingdom (Email: k.bhattacharya{at}ed.ac.uk).

Platypnea is characterized by breathlessness in the upright position. Orthodeoxia is defined by arterial desaturation on standing. Herein we describe a case of platypnea-orthodeoxia syndrome in a patient who underwent a right pneumonectomy for adenocarcinoma of the lung. Closure of a patent foramen ovale, causing a right-to-left shunt, with an Amplatzer device, produced immediate symptomatic relief.




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