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Ann Thorac Surg 2009;88:2001-2004. doi:10.1016/j.athoracsur.2009.05.042
© 2009 The Society of Thoracic Surgeons
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Mario Santini
Alfonso Fiorelli
Giovanni Vicidomini
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Case Reports

Intrathoracic Extramedullary Haematopoiesis Manifested as a Neoplastic Lesion Within Anterior Mediastinum

Mario Santini, MD*, Alfonso Fiorelli, MD, PhD, Giovanni Vicidomini, MD, PhD, Filomena Napolitano, MD

Thoracic Surgery Unit, Second University of Naples, Naples, Italy

Accepted for publication May 13, 2009.

* Address correspondence to Dr Santini, Thoracic Surgery Unit, Second University of Naples, Piazza Miraglia, 2, Naples, I-80138, Italy (Email: mario.santini{at}unina2.it).

Intrathoracic extramedullary hematopoiesis (EMH), the formation of apparently normal blood cells outside the confines of the bone marrow, is an uncommon but well-defined entity. It is usually associated with hematologic disorders and located in the lower paravertebral sulci or rarely in the pleura. We report a case of EMH, which presented in a patient without hematologic disorders and was manifested as an anterior mediastinal mass. The first interesting aspect of our case was that EMH occurred in a patient with normal laboratory findings and no past medical history of anemia. The second remarkable characteristic was that EMH manifested as an anterior mediastinal mass, mimicking a neoplastic lesion. Definitive diagnosis of EMH was established by a video-assisted thoracoscopic surgical biopsy. In light of this diagnosis, no further surgical procedure was carried out.






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