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Ann Thorac Surg 2009;88:1999-2001. doi:10.1016/j.athoracsur.2009.05.063
© 2009 The Society of Thoracic Surgeons
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Case Reports

Preoperative Embolization of Castleman's Disease Using Microspheres

Warren Swee, MD, MPHa, Ahmed M. Housseini, MDa,c, J. Fritz Angle, MDa,b,c,d, David R. Jones, MDb, Thomas M. Daniel, MDb, Ulku C. Turba, MDa, Ehab A. Abdel-Gawad, MDa,d, Klaus D. Hagspiel, MDa,*

a Department of Radiology, University of Virginia Health System, Charlottesville, Virginia
b Department of Surgery, University of Virginia Health System, Charlottesville, Virginia
c Department of Radiology, Suez Canal University, Ismailia, Egypt
d El-Menia University, Department of Radiology, El-Menia, Egypt

Accepted for publication May 15, 2009.

* Address correspondence to Dr Hagspiel, University of Virginia Health System, 1215 Lee St, Charlottesville, VA 22908 (Email: kdh2n{at}virginia.edu).

Castleman's disease is a rare form of lymph node hyperplasia most commonly presenting as a solitary hypervascular mediastinal mass. Surgical resection is the treatment of choice, but this can be associated with significant blood loss due to its hypervascularity. We report two cases with a preoperative diagnosis of mediastinal Castleman's disease in whom preoperative embolization with Trisacryl gelatin microspheres (Biosphere Medical, Rockland, MA) was performed. Compared with the literature, a decrease in the amount of perioperative bleeding was noted in both cases.






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