ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Ann Thorac Surg 2009;88:1609-1615. doi:10.1016/j.athoracsur.2009.06.039
© 2009 The Society of Thoracic Surgeons
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Varun Puri
Tracey Guthrie
Daniel Kreisel
Bryan F. Meyers
Right arrow Permission Requests
Google Scholar
Right arrow Articles by Puri, V.
Right arrow Articles by Meyers, B. F.
PubMed
Right arrow Articles by Puri, V.
Right arrow Articles by Meyers, B. F.
Related Collections
Right arrow Lung - transplantation

Original Articles: General Thoracic

Lung Transplantation and Donation After Cardiac Death: A Single Center Experience

Varun Puri, MDa, Masina Scavuzzo, RN, BSNa, Tracey Guthrie, RNa, Ramsey Hachem, MDb, Alexander S. Krupnick, MDa, Daniel Kreisel, MD, PhDa, G. Alexander Patterson, MDa, Bryan F. Meyers, MD, MPHa,*

a Department of Surgery, Washington University, St. Louis, Missouri
b Department of Medicine, Washington University, St. Louis, Missouri

Accepted for publication June 4, 2009.

* Address correspondence to Dr Meyers, Division of Cardiothoracic Surgery, Barnes-Jewish Hospital, Queeny Tower, 3108, One Barnes-Jewish Hospital Plaza, St. Louis, MO 63110 (Email: meyersb{at}wudosis.wustl.edu).

Presented at the Forty-fifth Annual Meeting of The Society of Thoracic Surgeons, San Francisco, CA, Jan 26–28, 2009.

Background: Lung donation after cardiac death (DCD) can enlarge the donor pool. Single-center reports have shown comparable outcomes after lung transplantation using conventional donors versus DCD in small numbers of patients.

Methods: We performed a retrospective review of DCD experience at a single lung transplant program using a prospective database.

Results: Between January 2003 and April 2008, 293 lung transplantations were performed, including 11 bilateral transplantations (3.7%) using DCD lungs. Similar criteria were used to assess donor quality. The hospital mortality for DCD recipients was 2 of 11 (18%) and overall mortality was 4 of 11 (36%) by 18 months of follow-up. Seven DCD patients (64%) are alive with a median follow-up of 32 months. The DCD group was comparable to the control group in age and ischemic times. The 4 deaths, when compared with 7 DCD survivors, had longer ischemic time (293 minutes versus 232 minutes) and a higher incidence of nonlocal donors (3 of 4 versus 1 of 7).

Conclusions: At our center, early outcomes after DCD lung transplantations are somewhat inferior to those of series from other centers but approach national averages for conventional lung transplantation. Thus, DCD lung transplantation has the potential to increase the donor pool but must be offered cautiously.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2009 by The Society of Thoracic Surgeons.