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Ann Thorac Surg 2009;88:1445-1449. doi:10.1016/j.athoracsur.2009.06.047
© 2009 The Society of Thoracic Surgeons
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Bhuvaneswari Krishnamoorthy
Paul Waterworth
Nizar Yonan
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Original Articles: Adult Cardiac

Randomized Prospective Study Comparing Conventional Subcuticular Skin Closure With Dermabond Skin Glue After Saphenous Vein Harvesting

Bhuvaneswari Krishnamoorthy, BSa,*, Osman Najam, MBChBb,*, Ursalan A. Khan, MBChBb, Paul Waterworth, FRCS (CTh)a, James E. Fildes, PhDb,c,*, Nizar Yonan, FRCS (CTh)a,b

a Department of Cardiothoracic Surgery, University Hospital of South Manchester NHS Foundation Trust, Manchester, United Kingdom
b The Transplant Centre, University Hospital of South Manchester NHS Foundation Trust, Manchester, United Kingdom
c The School of Translational Medicine, Faculty of Human and Life Sciences, University of Manchester, Manchester, United Kingdom

Accepted for publication June 18, 2009.

* Address correspondence to Dr Fildes, The Transplant Centre, University Hospital of South Manchester NHS Foundation Trust, Manchester, M23 9LT, United Kingdom (Email: james.fildes{at}manchester.ac.uk).

Background: Dermabond (Ethicon UK, Edinburgh, United Kingdom) is a topical skin adhesive used for surgical wound closure, with purported advantages over conventional sutures on cosmetic outcomes, cost benefits, and operative times. This study compared results of skin closure using Dermabond and subcuticular sutures after coronary artery bypass grafting (CABG).

Methods: The study prospectively enrolled and randomized 106 patients who underwent CABG. The groups received closure with Dermabond skin glue or subcuticular sutures (n = 53 each) after saphenous vein harvesting using the bridging technique. Wound closure time for the two methods was recorded. Cosmetic appearance was assessed using the Hollander, the Vancouver, and the visual analog scale. Patient satisfaction was recorded before discharge and at week 6.

Results: There were no significant differences in the total operative time between the two groups (p = 0.43). Closure time was significantly shorter in the Dermabond group (p = 0.017). Patients in the Dermabond group also reported superior cosmetic outcome at weeks 1 (p < 0.001) and 6 (p = 0.001) and improved patient satisfaction (p < 0.001).

Conclusions: Dermabond has demonstrated superiority over traditional subcuticular skin sutures in terms of closure time, cosmetic appearance, and patient satisfaction. This technique provides a novel method of wound closure after CABG.


Related Article

Invited Commentary
Ivar Risnes
Ann. Thorac. Surg. 2009 88: 1450. [Extract] [Full Text] [PDF]



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I. Risnes
Invited commentary.
Ann. Thorac. Surg., November 1, 2009; 88(5): 1450 - 1450.
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