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This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Amal K. Bose Jimmy Kim Fatt Hon Binayak Chanda Rakesh Uppal Simon Kendall Permission Requests Google Scholar Articles by Bose, A. K. Articles by Kendall, S. PubMed Articles by Bose, A. K. Articles by Kendall, S. Related Collections Valve disease

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Case Reports

Acute Fibrin Deposition Causing Acute Failure of Two Tissue Pericardial Valves

^a The James Cook University Hospital, Middlesbrough, United Kingdom
^b The London Chest Hospital, London, United Kingdom

Accepted for publication January 13, 2009.

^_* Address for correspondence to Dr Bose, Department of Cardiothoracic Surgery, The James Cook University Hospital, Marton Rd, Middlesbrough, TS4 3BW, United Kingdom (Email: amal{at}doctors.net.uk).

We report the early failure of two tissue valves within hours of surgery due to the accumulation of cellular debris in two different institutions in the United Kingdom. The valves were both found at explant to be covered in a cellular material — possibly fibrin. From clinical experience and careful review of the literature we have found no other reports of such early valve failure due to the build up of material on the structure of the valve. This rare occurrence needs to be reported in the literature to forewarn clinicians of an early complication that may not be recognized yet.