ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


Ann Thorac Surg 2009;88:362-371. doi:10.1016/j.athoracsur.2009.04.035
© 2009 The Society of Thoracic Surgeons

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
David P. Mason
Sreekumar Subramanian
Edward R. Nowicki
Sudish C. Murthy
Thomas W. Rice
Eugene H. Blackstone
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mason, D. P.
Right arrow Articles by Blackstone, E. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mason, D. P.
Right arrow Articles by Blackstone, E. H.
Related Collections
Right arrow Lung - cancer


Original Articles: General Thoracic

Impact of Smoking Cessation Before Resection of Lung Cancer: A Society of Thoracic Surgeons General Thoracic Surgery Database Study

David P. Mason, MDa,*, Sreekumar Subramanian, MDa, Edward R. Nowicki, MD, MSa, Joshua D. Grab, MSb, Sudish C. Murthy, MD, PhDa, Thomas W. Rice, MDa, Eugene H. Blackstone, MDa,c

a Department of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio
c Department of Quantitative Health Sciences, Research Institute, Cleveland Clinic, Cleveland, Ohio
b Duke Clinical Research Institute, Duke University, Durham, North Carolina

Accepted for publication April 1, 2009.

* Address correspondence to Dr Mason, Cleveland Clinic, Department of Thoracic and Cardiovascular Surgery, 9500 Euclid Ave, Mail Stop J4-1, Cleveland, OH 44195 (Email: masond2{at}ccf.org).

Presented at the Forty-fifth Annual Meeting of The Society of Thoracic Surgeons, San Francisco, CA, Jan 26–28, 2009.

Background: Smoking cessation is presumed to be beneficial before resection of lung cancer. The effect of smoking cessation on outcome was investigated.

Methods: From January 1999 to July 2007, in-hospital outcomes for 7990 primary resections for lung cancer in adults were reported to the Society of Thoracic Surgeons General Thoracic Surgery Database. Risk of hospital death and respiratory complications was assessed according to timing of smoking cessation, adjusted for clinical confounders.

Results: Hospital mortality was 1.4% (n = 109), but 1.5% in patients who had smoked (105 of 6965) vs 0.39% in those who had not (4 of 1025). Compared with the latter, risk-adjusted odds ratios were 3.5 (p = 0.03), 4.6 (p = 0.03), 2.6 (p = 0.7), and 2.5 (p = 0.11) for those whose timing of smoking cessation was categorized as current smoker, quit from 14 days to 1 month, 1 to 12 months, or more than 12 months preoperatively, respectively. Prevalence of major pulmonary complications was 5.7% (456 of 7965) overall, but 6.2% in patients who had smoked (429 of 6941) vs 2.5%% in those who had not (27 of 1024). Compared with the latter, risk-adjusted odds ratios were 1.80 (p = 0.03), 1.62 (p = 0.14), 1.51 (p = 0.20), and 1.29 (p = 0.3) for those whose timing of smoking cessation was categorized as above.

Conclusions: Risks of hospital death and pulmonary complications after lung cancer resection were increased by smoking and mitigated slowly by preoperative cessation. No optimal interval of smoking cessation was identifiable. Patients should be counseled to stop smoking irrespective of surgical timing.




This article has been cited by other articles:


Home page
Interact CardioVasc Thorac SurgHome page
M. Zaman, H. Bilal, S. Mahmood, and A. Tang
Does getting smokers to stop smoking before lung resections reduce their risk?
Interact CardioVasc Thorac Surg, December 6, 2011; (2011) ivr093v1.
[Abstract] [Full Text] [PDF]


Home page
Eur J Cardiothorac SurgHome page
B. Balduyck, P. Sardari Nia, A. Cogen, Y. Dockx, P. Lauwers, J. Hendriks, and P. Van Schil
The effect of smoking cessation on quality of life after lung cancer surgery
Eur J Cardiothorac Surg, December 1, 2011; 40(6): 1432 - 1438.
[Abstract] [Full Text] [PDF]


Home page
Arch Intern MedHome page
K. Myers, P. Hajek, C. Hinds, and H. McRobbie
Stopping Smoking Shortly Before Surgery and Postoperative Complications: A Systematic Review and Meta-analysis
Arch Intern Med, June 13, 2011; 171(11): 983 - 989.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Respir. Crit. Care Med.Home page
S. Raviv, K. A. Hawkins, M. M. DeCamp Jr., and R. Kalhan
Lung Cancer in Chronic Obstructive Pulmonary Disease: Enhancing Surgical Options and Outcomes
Am. J. Respir. Crit. Care Med., May 1, 2011; 183(9): 1138 - 1146.
[Abstract] [Full Text] [PDF]


Home page
Eur J Cardiothorac SurgHome page
J. C. Reeve, K. Stiller, L. Denehy, and K. M. McPherson
Reply to Agostini et al.
Eur J Cardiothorac Surg, April 1, 2011; 39(4): 612 - 613.
[Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
M. Shapiro, S. J. Swanson, C. D. Wright, C. Chin, S. Sheng, J. Wisnivesky, and T. S. Weiser
Predictors of Major Morbidity and Mortality After Pneumonectomy Utilizing The Society for Thoracic Surgeons General Thoracic Surgery Database
Ann. Thorac. Surg., September 1, 2010; 90(3): 927 - 935.
[Abstract] [Full Text] [PDF]


Home page
ChestHome page
R. A. Meguid, C. M. Hooker, J. Harris, L. Xu, W. H. Westra, J. T. Sherwood, M. Sussman, S. M. Cattaneo II, J. Shin, S. Cox, et al.
Long-term Survival Outcomes by Smoking Status in Surgical and Nonsurgical Patients With Non-small Cell Lung Cancer: Comparing Never Smokers and Current Smokers
Chest, September 1, 2010; 138(3): 500 - 509.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
K. G. Reyes, D. P. Mason, L. Thuita, E. R. Nowicki, S. C. Murthy, G. B. Pettersson, and E. H. Blackstone
Guidelines for Donor Lung Selection: Time for Revision?
Ann. Thorac. Surg., June 1, 2010; 89(6): 1756 - 1765.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Respir. Crit. Care Med.Home page
J. P. Sculier, T. Berghmans, and A. P. Meert
Update in Lung Cancer and Mesothelioma 2009
Am. J. Respir. Crit. Care Med., April 15, 2010; 181(8): 773 - 781.
[Full Text] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2009 by The Society of Thoracic Surgeons.