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Ann Thorac Surg 2009;88:271-273. doi:10.1016/j.athoracsur.2008.12.036
© 2009 The Society of Thoracic Surgeons
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Gordan Samoukovic
Renzo Cecere
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Right arrow Mechanical Circulatory Assistance
Right arrow Transplantation - heart

Case Reports

Successful Treatment of Heart Failure due to Acute Transplant Rejection With the Impella LP 5.0

Gordan Samoukovic, MDa, Talal Al-Atassi, BSca, Cristian Rosu, MDa, Nadia Giannetti, MDb, Renzo Cecere, MDa,*

a Division of Cardiothoracic Surgery, McGill University Health, Montreal, Quebec, Canada
b Division of Cardiology, McGill University Health, Montreal, Quebec, Canada

Accepted for publication December 1, 2008.

* Address correspondence to Dr Cecere, 687 Pine Ave West, Rm S8.45, Montreal, Quebec, H3A 1A1, Canada (Email: renzo.cecere{at}muhc.mcgill.ca).

Cardiogenic shock resulting from transplant rejection is a serious complication with high mortality and morbidity. Often resistant to maximal medical therapy, this condition frequently requires mechanical circulatory support until recovery or retransplantation. We present a 52-year-old patient with multiorgan failure secondary to acute graft rejection after orthotopic heart transplantation. Maximal medical therapy was not successful, and the patient was bridged to recovery with an Impella LP 5.0 (Abiomed Inc, Danvers, MA) left ventricular assist device (LVAD). The relative merits of this therapeutic approach are outlined and discussed. The patient was discharged 3 weeks after LVAD removal and remains clinically stable.




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