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Ann Thorac Surg 2009;87:1927-1928. doi:10.1016/j.athoracsur.2008.10.077
© 2009 The Society of Thoracic Surgeons
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Gaetano Rocco
Francesco Scognamiglio
Antonello La Rocca
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Case Reports

Primary Giant Clear Cell Sarcoma (Soft Tissue Malignant Melanoma) of the Sternum

Gaetano Rocco, MD, FRCS(Ed)a,*, Anna Rosaria de Chiara, MDc, Flavio Fazioli, MDb, Francesco Scognamiglio, MDa, Antonello La Rocca, MDa, Gaetano Apice, MDb, Carla Riva, PhDd

a Department of Thoracic Surgery and Oncology, National Cancer Institute, Pascale Foundation, IRCCS, Naples, Italy
b Sarcoma Multidisciplinary Team, National Cancer Institute, Pascale Foundation, IRCCS, Naples, Italy
c Department of Pathology, National Cancer Institute, Pascale Foundation, IRCCS, Naples, Italy
d Department of Pathology, National Cancer Institute, IRCCS, Milan, Italy

Accepted for publication October 27, 2008.

* Address correspondence to Dr Rocco, Department of Thoracic Surgery and Oncology, National Cancer Institute, Pascale Foundation, Via Semmola 81, Naples, 80131, Italy (Email: gaetano.rocco{at}btopenworld.com).

One case of a primary clear cell sarcoma of the sternum (also called soft tissue melanoma) is reported. This neoplasm represents a rare occurrence, and as a rule, differential diagnosis with melanoma often requires detailed immunohistochemistry and cytogenetic analysis (ie, rearrangement of EWS gene localized on 22q12 chromosome). Because wide resection is recommended, chest wall reconstruction may pose challenging technical issues. In our patient, we elected not to proceed to clavicular stabilization. Nevertheless, acceptable shoulder girdle mobility was observed after surgery.






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