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Ann Thorac Surg 2009;87:1925-1926. doi:10.1016/j.athoracsur.2008.10.062
© 2009 The Society of Thoracic Surgeons
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Kamal A. Mansour
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Case Reports

Primary Yolk Sac Tumor of the Lung

Abdel Rahman M. Abdel Rahman, MDa, Emad N. Ebied, MDb, Mohamed A. Nouh, MDc, Anthony A. Gal, MDd, Kamal A. Mansour, MDe,*

a Department of Surgery, National Cancer Institute, Cairo, Egypt
b Department of Pediatric Oncology, National Cancer Institute, Cairo, Egypt
c Department of Pathology, National Cancer Institute, Cairo, Egypt
d Department of Pathology, General Thoracic Section, Emory University, Atlanta, Georgia
e Department of Surgery, General Thoracic Section, Emory University, Atlanta, Georgia

Accepted for publication October 21, 2008.

* Address correspondence to Dr Mansour, Cardiothoracic Surgery, The Emory Clinic, 1365 Clifton Road, NE, Atlanta, Georgia 30322 (Email: kamal.mansour{at}emoryhealthcare.org).

Yolk-sac tumor mimics the yolk sac of the embryo, and the presence of alpha fetoprotein in the tumor cells is highly characteristic. We present an 18-year-old boy with primary pulmonary yolk-sac tumor diagnosed postoperatively. A computed tomographic scan revealed a huge intrathoracic soft tissue mass 20 x 25 cm occupying most of the left hemithorax. Two trials of computed tomographic-guided needle biopsy were nonconclusive. A left upper lobectomy was performed with a complete tumor resection. Postoperatively, the patient's alpha fetoprotein (AFP) was 10,512 IU/mL with gradual decline under chemotherapy. The patient is alive 10 months after surgery and is disease free.






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