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Ann Thorac Surg 2009;87:1275-1277. doi:10.1016/j.athoracsur.2008.08.028
© 2009 The Society of Thoracic Surgeons

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Jaime F. Vazquez-Jimenez
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Case Reports

Allergy to Pacemaker Silicone Compounds: Recognition and Surgical Management

Mihaela L. Oprea, MDa,*, Heike Schnöring, MDa, Jörg S. Sachweh, MDa, Hagen Ott, MDb, Julia Biertz, MDc, Jaime F. Vazquez-Jimenez, MDa

a Department of Pediatric Cardiac Surgery, RWTH Aachen University, Aachen, Germany
b Department of Dermatology, RWTH Aachen University, Aachen, Germany
c Department of Pediatric Cardiology, RWTH Aachen University, Aachen, Germany

Accepted for publication August 12, 2008.

* Address correspondence to Dr Oprea, University Hospital Aachen, Pauwelsstr. 30, Aachen, D-52074, Germany (Email: moprea{at}ukaachen.de).

Silicone is a widely used biomaterial. Contact allergy, particularly to silicone components of pacemaker coatings, is uncommon. We present a 12-year-old girl with a history of complex congenital heart disease and acquired complete heart block excluding transvenous lead placement. Contact allergy to silicone led to multiple surgical interventions until the etiology for recurrent pacemaker wound complications was discovered. The key to diagnosis was a specific manufacturer's patch test. Complete removal of the former pacing system and placement of custom-made silicone free pacemaker components and epicardial use of silicone free transvenous leads were essential for successful therapy.




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A. Kolodzinska, A. Kutarski, L. Koperski, M. Grabowski, B. Malecka, and G. Opolski
Differences in encapsulating lead tissue in patients who underwent transvenous lead removal
Europace, January 13, 2012; (2012) eur384v1.
[Abstract] [Full Text] [PDF]




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