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Ann Thorac Surg 2009;87:1264-1266. doi:10.1016/j.athoracsur.2008.08.052
© 2009 The Society of Thoracic Surgeons

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Case Reports

Treatment of Primary Melanoma of the Lung Monitored by 5-S-Cysteinyldopa Levels

Kei Shikuma, MD, Mitsugu Omasa, MD, PhD*, Yojiro Yutaka, MD, Masato Okuda, MD, PhD, Toshihiko Taki, MD, PhD

Division of Thoracic Surgery, Respiratory Disease Center, The Tazuke Kofukai Medical, Research Institute Kitano Hospital, Kita-ku, Osaka, Japan

Accepted for publication August 20, 2008.

* Address correspondence to Dr Omasa, Division of Thoracic Surgery, Respiratory Disease Center, The Tazuke Kofukai Medical Research Institute Kitano Hospital, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan (Email: m-oomasa{at}kitano-hp.or.jp).

Malignant melanoma originating outside the skin is very rare, whereas primary malignant melanoma of the lung is extremely rare. 5-S-Cysteinyldopa (5-S-CD), a melanin metabolite, has been reported to be a prognostic marker for cutaneous malignant melanoma. This is the first report in the English language literature dealing with primary malignant melanoma of the lung using serum 5-S-Cysteinyldopa levels to monitor the effects of surgery and chemotherapy.







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