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Ann Thorac Surg 2009;87:977-984. doi:10.1016/j.athoracsur.2008.08.018
© 2009 The Society of Thoracic Surgeons
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Shanda H. Blackmon
David C. Rice
Reza Mehran
Jon-Cecil Walkes
Garrett L. Walsh
Harsh Singh
Ara A. Vaporciyan
Michael Reardon
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Review

Management of Primary Pulmonary Artery Sarcomas

Shanda H. Blackmon, MD, MPHa,b,c,d,*, David C. Rice, MMB, BChc, Arlene M. Correa, PhDc, Reza Mehran, MDc, Joe B. Putnam, MDc, W. Roy Smythe, MDc, Jon-Cecil Walkes, MDb,d, Garrett L. Walsh, MDc, Cesar Moran, MDc, Harsh Singh, MDe, Ara A. Vaporciyan, MDc, Michael Reardon, MDb,d

a The Methodist Hospital, Department of Surgery, MD Anderson Cancer Center, Houston, Texas
b The Methodist DeBakey Heart Center, MD Anderson Cancer Center, Houston, Texas
c The University of Texas MD Anderson Cancer Center, Houston, Texas
e Christchurch, Canterbury, New Zealand
d Weill Medical College of Cornell University, New York, New York

* Address correspondence to Dr Blackmon, 6550 Fannin St, Smith Tower Ste 1661, Houston, TX 77030 (Email: shblackmon{at}tmhs.org).

The objective of this review is to determine the outcome of patients with sarcomas involving the main pulmonary artery, pulmonic valve, or right ventricular outflow tract. Survival data were analyzed using an aggregate series derived from the published literature in conjunction with a current series. Median survival was 36.5 ± 20.2 months for patients undergoing an attempt at curative resection compared with 11 ± 3 months for those undergoing incomplete resection. Median survival was 24.7 ± 8.5 months for patients undergoing multimodality treatment compared with 8.0 ± 1.7 months for patients having single-modality therapy. A complete review of diagnosis, evaluation, treatment, and surveillance of primary pulmonary artery sarcomas follows.




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