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Case Reports

Placental Transmogrification of the Lung Presenting as a Small Solitary Nodule

^a Department of Thoracic Surgery, Saitama Cardiovascular and Respiratory Center, Saitama, Japan
^b Department of Pathology, Saitama Cardiovascular and Respiratory Center, Saitama, Japan
^c Department of Pathology and Laboratory Medicine, Mayo Clinic Scottsdale, Scottsdale, Arizona

Accepted for publication July 9, 2008.

^_* Address correspondence to Dr Saito, Department of Thoracic Surgery, Saitama Cardiovascular and Respiratory Center, 1696, Itai, Kumagaya, Saitama, 360-0105, Japan (Email: k3699004{at}pref.saitama.lg.jp).

Placental transmogrification of the lung is a rare cystic lesion of the lung, which has some histologic resembling to placental tissue. Placental transmogrification of the lung has been considered a variant of unilateral bullous emphysema, but in our case, the patient was a 47-year-old man who had no coexisting emphysema of the lung. Histologically our case showed an interstitial proliferation of clear cells with cystic change interpreted as secondary; we also agree with our colleagues that this proliferation may be the primary event pathogenetically. Surgical resection of this lesion seems to be curative.