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Ann Thorac Surg 2009;87:e13-e14. doi:10.1016/j.athoracsur.2008.09.046
© 2009 The Society of Thoracic Surgeons

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Russell W.J. Millner
Christos Alexiou
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Right arrow Cardiac - pharmacology


Case Reports

A New Hemostatic Agent: Initial Life-Saving Experience With Celox (Chitosan) in Cardiothoracic Surgery

Russell W.J. Millner, MD, FRCS (CTh)a,*, Alan S. Lockhart, FRCAb, Helen Bird, FRCAb, Christos Alexiou, PhD, FRCS (CTh)a

a Department of Cardiothoracic Surgery, Blackpool Victoria Hospital, Blackpool, United Kingdom
b Department of Cardiothoracic Anesthesia, Blackpool Victoria Hospital, Blackpool, United Kingdom

Accepted for publication September 11, 2008.

* Address correspondence to Dr Millner, Department of Cardiothoracic Surgery, Blackpool Victoria Hospital, Whinney Heys Rd, Blackpool, FY3 8NR, United Kingdom (Email: russellmillner{at}btinternet.com).

Celox (MedTrade Products Ltd, Cheshire, UK) is a proprietary preparation of chitosan, indicated for moderate to severe hemorrhage and currently used for hemostasis in the emergency and military settings. We describe its lifesaving use in 2 patients undergoing cardiothoracic surgery in which conventional techniques had failed.




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