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Ann Thorac Surg 2009;87:597-601. doi:10.1016/j.athoracsur.2008.09.004
© 2009 The Society of Thoracic Surgeons
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New Technology

Off-Pump Pulmonary Valve Implantation of a Valved Stent With an Anchoring Mechanism

Guo-Wei Meng, MDa,b, Jian-Ye Zhou, PhDa, Yue Tang, MD, PhDa, Zan-Kai Ye, MDa, Yan Zhang, MDa, Guang-Mao Liu, MDa, Sheng-Shou Hu, MDa,*

a Key Laboratory of the Cardiovascular Regenerative Medicine, Ministry of Health, Fu Wai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, Peoples Republic of China
b Department of Cardiovascular Surgery, Second Hospital of Shandong University, Shandong University, Jinan, Peoples Republic of China

Accepted for publication September 4, 2008.

* Address correspondence to Dr Hu, Key Laboratory of the Cardiovascular Regenerative Medicine, Ministry of Health, Fu Wai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100037, Peoples Republic of China (Email: shengshouhu{at}yahoo.com).

Purpose: The purpose of this study was to evaluate the longitudinal performance and anti-migration effect of a bovine valved stent equipped with an anchoring mechanism implanted off-pump in the pulmonary position.

Description: Through a delivery system, the bell-shaped pulmonary valved stents were implanted off-pump in the pulmonary valve position into six sheep by the transventricular approach. Hemodynamic, angiographic, and echocardiographic evaluations were carried out before, immediately after, and 2 months after implantation. Macroscopic and radiographic examination were performed for evaluation.

Evaluation: The valved stents were all successfully implanted off-pump in the pulmonary position on six sheep. Early and late angiographic, echocardiographic, hemodynamic, and macroscopic studies confirmed firm anchoring and good positions of the stents. All valved stents were potent, except one mild stenosis with a 24 mm Hg transvalvular pressure gradient that developed and one mild insufficiency that were discovered at the end of the study.

Conclusions: Transventricular implantation of the bell-shaped pulmonary valved stents was evaluated during a 2-month period in the sheep in the present study and showed a good structural and functional outcome with no migration.


Related Article

Invited Commentary
Georg Lutter and Jochen Cremer
Ann. Thorac. Surg. 2009 87: 601-602. [Extract] [Full Text] [PDF]



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G. Lutter and J. Cremer
Invited commentary.
Ann. Thorac. Surg., February 1, 2009; 87(2): 601 - 602.
[Full Text] [PDF]


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