|
|
||||||||
Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan
Accepted for publication September 23, 2008.
* Address correspondence to Dr Okamura, Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho Omiya-ku Saitama-shi, Saitama, 330-8503, Japan (Email: homareokamura{at}hotmail.co.jp).
Background: When aortic valve replacement is performed in patients with a small aortic annulus, prosthesis–patient mismatch is of concern. Such prosthesis–patient mismatch may affect postoperative clinical status and survival. We investigated the outcomes of isolated aortic valve replacement performed with a 17-mm mechanical prosthesis in patients with aortic stenosis.
Methods: Twenty-three patients with aortic stenosis (mean age, 74.6 ± 6.3 years) underwent isolated aortic valve replacement with a 17-mm St. Jude Medical Regent prosthesis. Mean body surface area was 1.41 ± 0.13 m2. Preoperative echocardiography yielded a mean aortic valve area of 0.36 ± 0.10 cm2/m2, a mean left ventricular–aortic pressure gradient of 68.4 ± 25.3 mm Hg, and a mean left ventricular mass index of 200 ± 69 g/m2.
Results: There was no operative mortality, and there were no valve-related events. Echocardiography at 14.0 ± 10.0 months after aortic valve replacement showed a significant increase in the mean effective orifice area index (0.95 ± 0.24 cm2/m2), decrease in the mean left ventricular–aortic pressure gradient (17.4 ± 8.2 mm Hg), and decrease in the mean left ventricular mass index (124 ± 37 cm2/m2). Prosthesis–patient mismatch (effective orifice area index < 0.85 cm2/m2) was present in 8 patients at discharge. In these patients as well as in those without prosthesis–patient mismatch, the left ventricular mass index decreased remarkably during follow-up.
Conclusions: Aortic valve replacement with a 17-mm Regent prosthesis appears to provide satisfactory clinical and hemodynamic results in patients with a small aortic annulus. Remarkable left ventricular mass regression during follow-up was achieved irrespective of the effective orifice area index at discharge.
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |