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Ann Thorac Surg 2008;86:1686-1688. doi:10.1016/j.athoracsur.2008.04.060
© 2008 The Society of Thoracic Surgeons

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Case Reports

Intrabronchial Foreign Body Extracted With Tranilast and Corticosteroid

Yasuji Terada, MDa,*, Yasuto Sakaguchi, MDa, Tomoya Kono, MDa, Jun Nohara, MDb, Tetsuo Noguchi, MDb

a Department of Thoracic Surgery, Nagahama City Hospital, Nagahama, Japan
b Department of Respiratory Medicine, Nagahama City Hospital, Nagahama, Japan

Accepted for publication April 16, 2008.

* Address correspondence to Dr Terada, Department of Thoracic Surgery, Nagahama City Hospital, 313 Oinui-cho, Nagahama, 526-8580, Japan (Email: yaterada{at}ex.biwa.ne.jp).

We present a case of intrabronchial foreign body buried in granulation tissue, which was successfully extracted administrating tranilast (n-[3,4-dimethoxycinnamoyl] anthranilic acid), suppressing collagen synthesis by fibroblasts in keloid and hypertrophic scars, and corticosteroid. Bronchoscopy of a 74-year-old man showed the nail was buried in reactive granulation tissue and could not be observed from the surface. Tranilast at 300 mg/day and methylprednisolone at 250 mg/day were prescribed for 4 days, followed by a reduction of the corticosteroid to 40 mg/day for 3 days. Seven days later, the granulation tissue and mucosal edema were diminished, and the nail was successfully extracted.







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