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Ann Thorac Surg 2008;86:1620-1625. doi:10.1016/j.athoracsur.2008.07.006
© 2008 The Society of Thoracic Surgeons

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Francis Fynn-Thompson
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Original Articles: Pediatric Cardiac

Video-Assisted Thoracoscopic Cardiac Denervation: A Potential Novel Therapeutic Option for Children With Intractable Ventricular Arrhythmias

Joseph Atallah, MDa, Francis Fynn-Thompson, MDb, Frank Cecchin, MDa, Daniel J. DiBardino, MDb, Edward P. Walsh, MDa, Charles I. Berul, MDa,*

a Department of Cardiology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts
b Department of Cardiac Surgery, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts

Accepted for publication July 1, 2008.

* Address correspondence to Dr Berul, Department of Cardiology, Children's Hospital Boston, 300 Longwood Ave, Boston, MA 02115 (Email: charles.berul{at}cardio.chboston.org).

Background: Left cardiac sympathetic denervation is one of the therapeutic modalities used in the management of patients with medically refractory long QT syndrome. Traditionally, a thoracotomy or cervical incision has been used as the standard surgical approach for performing left cardiac sympathetic denervation. Video-assisted thoracoscopic surgery allows a minimally invasive technique. There is only one published series on the use of video-assisted thoracoscopic surgery for left cardiac sympathetic denervation in patients with long QT syndrome.

Methods: We performed a retrospective clinical review of pertinent medical records and report a series including 9 pediatric patients (4 long QT syndrome, 4 catecholaminergic polymorphic ventricular tachycardia, and 1 idiopathic ventricular tachycardia) who underwent a left cardiac sympathetic denervation by means of video-assisted thoracoscopic surgery.

Results: There were no severe complications, and 6 of 7 symptomatic patients with available follow-up experienced marked improvement in the first month after sympathectomy.

Conclusions: This minimally invasive procedure provides a safe novel therapeutic option for children with drug-refractory catecholaminergic polymorphic ventricular tachycardia and other catecholamine-triggered arrhythmias.







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