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Ann Thorac Surg 2008;86:1343-1347. doi:10.1016/j.athoracsur.2008.06.026
© 2008 The Society of Thoracic Surgeons
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Cynthia D. Myers
John W. Brown
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Right arrow Congenital - cyanotic

New Technology

Performance of a 3-Bladed Propeller Pump to Provide Cavopulmonary Assist in the Failing Fontan Circulation

Amy L. Throckmorton, PhD, Kimberly K. Ballman, BA, Cynthia D. Myers, MD, Steven H. Frankel, PhD, John W. Brown, MD, Mark D. Rodefeld, MD*

Section of Cardiothoracic Surgery, Department of Surgery, Indiana University School of Medicine, Indianapolis, and Department of Mechanical Engineering, Purdue University School of Engineering, West Lafayette, Indiana

Accepted for publication June 5, 2008.

* Address correspondence to Dr Rodefeld, Section of Cardiothoracic Surgery, Indiana University School of Medicine, Emerson Hall 215, 545 Barnhill Dr, Indianapolis, IN 46202 (Email: rodefeld{at}iupui.edu).

Presented at the Poster Session of the Forty-fourth Annual Meeting of The Society of Thoracic Surgeons, Fort Lauderdale, FL, January 28–30, 2008.

Purpose: We hypothesized that a propeller pump design would function optimally to provide cavopulmonary assist in a univentricular Fontan circulation.

Description: The hydraulic and hemolysis performance of a rigid three-bladed propeller prototype (similar to a folding propeller design) was characterized. Pressure and flow measurements were taken for flow rates of 0.5 to 3 liters per minute (LPM) for 5,000 to 7,000 revolutions per minute (RPM) using a blood analog fluid. Hemolysis testing was performed using fresh bovine blood for 2 LPM at 6,000 RPM for a 6-hour duration.

Evaluation: The prototype performed well over the design operating range by producing a pressure rise of 5 to 50 mm Hg. Plasma free hemoglobin concentration remained less than 15 mg/dL. The normalized index of hemolysis peaked during the first hour, and then remained less than 10 mg/dL thereafter.

Conclusions: A propeller pump has the pressure-flow characteristics and minimal risk of hemolysis and venous pathway obstruction which make it ideal for temporary cavopulmonary assist. This type of device has the potential to provide a new therapeutic option for patients with failing univentricular Fontan physiology as a bridge-to-recovery or transplantation.




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F. G. Lacour-Gayet, C. J. Lanning, S. Stoica, R. Wang, B. A. Rech, S. Goldberg, and R. Shandas
An artificial right ventricle for failing fontan: in vitro and computational study.
Ann. Thorac. Surg., July 1, 2009; 88(1): 170 - 176.
[Abstract] [Full Text] [PDF]


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