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Ann Thorac Surg 2008;86:622-626. doi:10.1016/j.athoracsur.2008.03.009
© 2008 The Society of Thoracic Surgeons
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Peter M. Alison
Kirsten A. Finucane
Justin Negri
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Right arrow Mechanical Circulatory Assistance

New Technology

Pediatric Experience With the VentrAssist LVAD

Peter N. Ruygrok, MDa,*, Don S. Esmore, MBBSb, Peter M. Alison, MBChBa, Kirsten A. Finucane, MBChBa, Shay P. McGuinness, MBChBa, Alastair D. McGeorge, MBChBa, Justin Negri, MBBSb, Kylie Jones, RNb, Helen C. Gibbs, RNa

a New Zealand Heart and Lung Transplant Service, Auckland City Hospital, Auckland, New Zealand
b Heart Transplant Service, The Alfred Hospital, Melbourne, Australia

Accepted for publication March 5, 2008.

* Address correspondence to Dr Ruygrok, Green Lane Cardiovascular Service, Level 3, Auckland City Hospital, Private Bag 92024, Auckland, 1030, New Zealand (Email: pruygrok{at}adhb.govt.nz).

Purpose: The purpose of this study is to describe the first experience of implanting a new left ventricular assist device in pediatric patients with end-stage heart failure.

Description: In two recent prospective, international, multicenter clinical trials, three children (aged ≤ 16 years) were implanted successfully with the VentrAssist (Ventracor Limited, Chatswood, Australia), a relatively small, novel, continuous flow, third-generation left ventricular assist device.

Evaluation: Despite the patients' disease severity (each child was in extremis at the time of implantation), VentrAssist (Ventracor Limited) implantation enabled each patient to be discharged home from the hospital. All patients survived for more than 1 year. One patient was successfully transplanted and another was bridged to an adequate degree of recovery; unfortunately, the third patient died on postoperative day 375 while waiting for a suitable donor heart. Consistent with the complications associated with left ventricular assist devices in adults, the main complications in these pediatric patients were infection and thromboembolism.

Conclusions: The VentrAssist may provide a major advancement in the management of larger children and adolescents with end-stage heart failure.




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F. Nicolini and T. Gherli
Alternatives to transplantation in the surgical therapy for heart failure
Eur. J. Cardiothorac. Surg., February 1, 2009; 35(2): 214 - 228.
[Abstract] [Full Text] [PDF]


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