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Case Reports

An Unusual Case of Giant Mediastinal Teratoma With Malignant Transformation

^a Department of General Thoracic Surgery, Tongji University-Affiliated Shanghai Pulmonary Hospital, Shanghai, China
^b Department of Pathology, Tongji University-Affiliated Shanghai Pulmonary Hospital, Shanghai, China
^c Department of Radiology, Tongji University-Affiliated Shanghai Pulmonary Hospital, Shanghai, China

Accepted for publication July 27, 2007.

^_* Address correspondence to Dr Chen, Zhengmin RD 507, Shanghai, 200433, China (Email: chenchang{at}nju.org.cn).

Mediastinal teratoma with malignant transformation is extremely rare. It consists of two components: (1) a pre-existing mature teratoma and (2) a nongerm cell malignant tumor. The radiologic appearances are usually straightforward, including a cystic mass and findings suggestive of malignancy. The authors describe an unusual case of giant mediastinal teratoma with malignant transformation in a 59-year-old patient. Radiographically, multiple spherical nodules appeared in the cyst that necessitated differentiation from hydatid disease. Computed tomography, magnetic resonance imaging, and operative and pathologic findings are provided.