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Ann Thorac Surg 2008;85:1483-1489. doi:10.1016/j.athoracsur.2007.10.042
© 2008 The Society of Thoracic Surgeons
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Saina Attaran
Lindsay John
Ahmed El-Gamel
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Right arrow Cardiac - pharmacology

Reviews

Clinical and Potential Use of Pharmacological Agents to Reduce Radial Artery Spasm in Coronary Artery Surgery

Saina Attaran, MD, Lindsay John, MD*, Ahmed El-Gamel, MD

Department of Cardiothoracic Surgery, Kings College Hospital, London, United Kingdom

* Address correspondence to Dr John, Department of Cardiothoracic Surgery, Kings College Hospital, Denmark Hill, London, SE5 9RS, United Kingdom (Email: lindsay.john{at}kch.nhs.uk).

The radial artery has increased in popularity as a conduit for use in coronary artery bypass surgery. However, concerns remain regarding the risk of radial artery spasm. Although the use of different pharmacological agents to prevent and treat this has been described, there is currently no clear agreement as to the optimal agent. To clarify which agents are most suitable for clinical use, all pertinent studies to date (January 2007) that have reported the efficacy of pharmacological agents in the prevention and treatment of radial artery spasm have been reviewed. It can be argued that verapamil–glycerine tri-nitrate solution represents the optimum agent when used in the perioperative period.




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