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The Statistician's Page

Measuring Follow-Up Completeness

^a Medical Data Research Center, Providence Health System, Portland, Oregon
^b Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands

^_* Address correspondence to Dr Wu, 9205 SW Barnes Rd, Suite 33, Portland, OR 97225 (Email: yingxing.wu{at}providence.org).

Completeness of follow-up is often used as a measure of the quality of follow-up, but the method used to compute it is often not declared. An ideal measure should be based on follow-up years instead of patients. Clark, Altman, and De Stavola proposed such a measure, called "C", which is the percentage of the maximum possible follow-up years, as of a given date, that has actually been accounted for or observed. However, such a measure will underestimate the true completeness, because the denominator (maximum possible follow-up years) does not account for unobserved patient deaths occurring before that date, and therefore, it is realistically unachievable. We propose a modification, C*, of Clark’s C, which accounts for the effect of unobserved patient deaths in attenuating the maximum potential follow-up, and thus gives a higher percentage for achieved follow-up completeness. We validated this theoretical improvement by comparing the values of C and C* computed for our long-term coronary artery bypass graft patients to the true completeness, which was obtained by using the National Death Index to complete our missing follow-up data. Using Clark’s C, the follow-up completeness was 80.4% and using our C* it is 84.5%, whereas the true follow-up completeness based on National Death Index information was 85.0%.

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