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Case Reports

Esophageal Carcinosarcoma With Basaloid Squamous Cell Carcinoma and Osteosarcoma

^a Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan
^b Department of Surgery, Cathay General Hospital, School of Medicine, Fu Jen Catholic University, Taipei, Taiwan
^c Department of Pathology, Taipei Veterans General Hospital, and School of Medicine, National Yang-Ming University, Taipei, Taiwan
^d Division of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, and School of Medicine, National Yang-Ming University, Taipei, Taiwan

Accepted for publication September 4, 2007.

^_* Address correspondence to Dr Hsu, Division of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Rd, Taipei, 112, Taiwan (Email: whhsu{at}vghtpe.gov.tw).

Carcinosarcoma of the esophagus is a rare malignant neoplasm. It often presents as a large intraluminal polypoid tumor with early onset of symptoms resulting in prompt diagnosis. We present here the first case of a carcinosarcoma of the esophagus that had a basaloid squamous cell carcinoma component in addition to the osteosarcoma and without a transitional zone. A 57-year-old man was diagnosed with a polypoid tumor in middle third of the esophagus causing dysphagia. Local recurrence and solitary pulmonary metastasis occurred 16 and 30 months after initial excision of the tumor, respectively. Prompt and aggressive surgical resection is mandatory for carcinosarcoma of the esophagus.