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a Department of Radiation Oncology, Mount Sinai School of Medicine, New York, New York
b Department of Cardiothoracic Surgery, Mount Sinai School of Medicine, New York, New York
c Department of Dermatology, Mount Sinai School of Medicine, New York, New York
d Department of Community & Preventive Medicine, Mount Sinai School of Medicine, New York, New York
e Department of Radiation Oncology, New York University School of Medicine, New York, New York
f Heart Lung and Esophageal Surgery Institute, University of Pittsburgh, Pittsburgh, Pennsylvania
g Department of Cardiothoracic Surgery, Boston Medical Center, Boston, Massachusetts
* Address correspondence to Dr Cesaretti, Mount Sinai School of Medicine, 1184 5th Ave, Box 1236, New York, NY 10029 (Email: jamie.cesaretti{at}msnyuhealth.org).
Presented at the Minimally Invasive Thoracic Surgery Summit, New York, NY, June 8–9, 2007.
Radiosurgery for lung cancer is a novel and promising concept that warrants thorough review. Stereotactic body radiotherapy enables the selective delivery of an intense dose of high-energy radiation to destroy a tumor with precise targeting. The radiobiology and physics behind the use of radiosurgery are presented, followed by a discussion of promising retrospective and prospective clinical data that has been reported from Japan, Europe, and the United States. The article closes with a discussion of multidisciplinary approaches that include radiosurgery which are on the therapeutic horizon.
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