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Original Articles: Cardiovascular

Novel Approach to Right Ventricular Outflow Tract Reconstruction Using a Stentless Porcine Valve

^a Department of Cardiac Surgery, California Pacific Medical Center, San Francisco, California
^b Department of Clinical Research, California Pacific Medical Center, San Francisco, California

Accepted for publication August 9, 2007.

^_* Address correspondence to Dr Black, Pediatric Cardiac Surgery, California Pacific Medical Center, 2100 Webster St, Suite 511, San Francisco, CA 94115 (Email: blackm{at}sutterhealth.org).

Presented at the Poster Session of the Forty-second Annual Meeting of The Society of Thoracic Surgeons, Chicago, IL, Jan 30–Feb 1, 2006.

Background: The use of a stentless aortic bioprosthesis offers the advantages of a larger effective valve orifice size, reduced transvalvular gradients, and improved hemodynamics versus stented valves. We hypothesized that these features would make the Toronto stentless porcine valve a preferred choice for patients with congenital abnormalities of the right ventricular outflow tract.

Methods: We retrospectively reviewed medical records of 21 patients with tetralogy of Fallot who subsequently underwent right ventricular outflow tract reconstruction during a 6-year period.

Results: The majority of patients received a 29-mm valve (n = 13), 5 received a 27-mm valve, with 1 each additional implant of a 19-, 22-, and 23-mm prosthesis. The mean age and weight were 24.5 years (range, 7 to 54 years) and 55.6 kg (range, 13.9 to 98.0 kg), respectively. Preoperatively, all patients had severe pulmonary insufficiency, mixed with mild to moderate stenosis in 2. The duration of postoperative echocardiographic follow-up ranged from 10 to 70 months (mean, 37.7 months). At the time of most recent follow-up, pulmonary insufficiency was graded as zero to trace in 47.4% (9 of 19 patients), mild in 42.1% (8 of 19 patients), and moderate in 10.5%, with 6 patients (31.6%) having concomitant pulmonary stenosis. The most recent mean and peak transvalvular gradients averaged 17.4 mm Hg (range, 11 to 24 mm Hg) and 26 mm Hg (range, 13 to 42 mm Hg), respectively. There have been no valve-related complications or explants, with one late death as a result of a noncardiac cause.

Conclusions: The stentless porcine valve is well suited for valve replacement in children, adolescents, and adults with congenital abnormalities of the right ventricular outflow tract, regardless of patient or valve size, particularly when significant downstream hemodynamic abnormalities exist.

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				J. A. Hawkins, C. T. Sower, L. M. Lambert, P. C. Kouretas, P. T. Burch, A. K. Kaza, M. D. Puchalski, and A. T. Yetman Stentless porcine valves in the right ventricular outflow tract: improved durability? Eur. J. Cardiothorac. Surg., April 1, 2009; 35(4): 600 - 605. [Abstract] [Full Text] [PDF]