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Ann Thorac Surg 2007;84:2095-2097. doi:10.1016/j.athoracsur.2007.06.070
© 2007 The Society of Thoracic Surgeons
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Case Reports

Good Syndrome Coexisting With Leukopenia

Masatsugu Ohuchi, MDa,*, Shuhei Inoue, MD, PhDa, Jun Hanaoka, MD, PhDb, Tomoyuki Igarashi, MDa, Noriaki Tezuka, MD, PhDb, Yoshitomo Ozaki, MD, PhDb, Koji Teramoto, MD, PhDb

a Department of Thoracic Surgery, National Hospital Organization Shiga Hospital, Shiga, Japan
b Department of Thoracic Surgery, National University Corporation, Shiga University of Medical Science, Shiga, Japan

Accepted for publication June 25, 2007.

* Address correspondence to Dr Ohuchi, Department of Thoracic Surgery, National Hospital Organization Shiga Hospital, 255 Gochi-cho, Higashi-ohmi-shi, Shiga, 527-8505, Japan (Email: iky10{at}shiga-hp.jp).

A 61-year-old man was admitted to our hospital for further examinations of a mediastinal mass. He had underwent an extended thymothymectomy, and had a tumor that was diagnosed as a type B1 thymoma, according to the World Health Organization. One year after surgery he was admitted again for recurrent diarrhea and pneumonia. Laboratory data revealed severe hypogammaglobulinemia with leukopenia. He was diagnosed with Good syndrome with leukopenia. Regular gamma globulin and figrastim injections were successful in keeping the patient symptom free. The prognosis of patients with Good syndrome and leukopenia is very poor; therefore, immediate diagnosis is important. The development of infectious diseases in a patient with thymoma or after the resection of thymoma mandates early and comprehensive immunologic investigation.






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