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Ann Thorac Surg 2007;84:1349-1355
© 2007 The Society of Thoracic Surgeons

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Original Articles: Cardiovascular

Clinical and Psychosocial Follow-Up Study of Children Treated With Extracorporeal Membrane Oxygenation

^a Department of Anaesthesiology, Rikshospitalet-Radiumhospitalet Medical Centre, Oslo, Norway
^b Department of Thoracic and Cardiovascular Surgery, Rikshospitalet-Radiumhospitalet Medical Centre, Oslo, Norway
^c Department of Pediatrics, Rikshospitalet-Radiumhospitalet Medical Centre, Oslo, Norway
^d Division of Child and Adolescent Psychiatry, Radiology, and Neurology, Rikshospitalet-Radiumhospitalet Medical Centre, Oslo, Norway

Accepted for publication May 4, 2007.

^_* Address correspondence to Dr Wagner, Department of Anaesthesiology, Rikshospitalet-Radiumhospitalet Medical Centre, Oslo, 0027, Norway (Email: kari.wagner{at}rikshospitalet.no).

Background: Serious heart and pulmonary failure may be treated with extracorporeal membrane oxygenation (ECMO). The aim of this follow-up study was a multimodal assessment of outcome in children surviving ECMO at our hospital from 1991 to 2004.

Methods: Twenty-two children were, on average, 1.18 years old (SD = 1.92; range, 0.1 to 7.8) when ECMO was initiated. Average age at follow-up was 7.2 years (range, 1.8 to 13.9). Thirteen children were treated for cardiac and nine for pulmonary failure. Venoarterial ECMO was performed in 21 patients and venovenous ECMO in one patient. The protocol included a review of patients records, clinical, neurologic and neuropsychologic, and radiological examinations, electroencephalogram, and interviews with the parents.

Results: Moderate or severe impairment in at least two clinical assessments were found in 16 (72.7%) children. Five (22.7%) children had cerebral palsy and 15 (68.2%) had moderate or severe cognitive impairment. Eight (36%) children had pathological radiologic findings. Pathological electroencephalograms were found in 11 (50%) patients including four (18.2%) with epileptic activity. Children with radiologic findings had a slightly worse cognitive outcome. There was no association between the neurophysiologic findings and the neuropsycohologic performance or the radiologic findings. Based on parental assessment, only four children had pathological scores.

Conclusions: All children, except for two, came walking to the follow-up visit. All parents were positive to the ECMO treatment, and reported a good or slightly reduced quality of life for their child. Cerebral sequelae were frequently found in children treated with ECMO. The need for treatment and support should be assessed in order to optimize their physical and psychosocial functioning.

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Ann. Thorac. Surg. 84: 1356-1356. [Full Text]

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				K. R. Kanter Invited commentary Ann. Thorac. Surg., October 1, 2007; 84(4): 1356 - 1356. [Full Text] [PDF]