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Ann Thorac Surg 2007;83:2197-2199
© 2007 The Society of Thoracic Surgeons

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Case Reports

Nodular Lymphoid Hyperplasia of the Lung: A Very Rare Disease Entity

^a Department of Surgery, Yamanashi Prefectural Central Hospital, Yamanashi, Japan
^b Department of Pathology, Yamanashi Prefectural Central Hospital, Yamanashi, Japan

Accepted for publication December 28, 2006.

^_* Address correspondence to Dr Sakurai, Department of Surgery, Yamanashi Prefectural Central Hospital, 1-1 Fujimi 1-chome, Kofu, Yamanashi, 400-0027, Japan (Email: sakuraihm{at}ybb.ne.jp).

Nodular lymphoid hyperplasia of the lung is an uncommon disease that is considered to be a benign lesion of a polyclonal lymphoid proliferation. Because of its rarity, little is known about the clinicopathologic characteristics of nodular lymphoid hyperplasia. Some researchers have questioned whether nodular lymphoid hyperplasias are truly reactive or are marginal zone B-cell lymphomas (low-grade lymphomas of mucosa-associated lymphoid tissue) mimicking reactive lymphoid processes. We present the case of a 67-year-old woman with nodular lymphoid hyperplasia of the lung and discuss the current knowledge concerning nodular lymphoid hyperplasias.