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Ann Thorac Surg 2007;83:1888-1891
© 2007 The Society of Thoracic Surgeons

Case Reports

Methicillin-Resistant Staphylococcus Aureus Pneumonia After Thoracic Surgery: Successful Treatment With Linezolid After Failed Vancomycin Therapy

Daniel Salerno, MD, Bobbak Vahid, MD*, Paul E. Marik, MD, FCCM

Department of Pulmonary and Critical Care Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania

Accepted for publication November 20, 2006.

* Address correspondence to Dr Vahid, Thomas Jefferson University Hospital, 834 Walnut St, Suite 650, Philadelphia, PA 19107 (Email: bobbak.vahid{at}mail.tju.edu).

We describe 3 patients with methicillin-resistant Staphylococcus aureus, hospital-acquired pneumonia who demonstrated a microbiological and clinical failure with vancomycin despite adequate trough levels. All 3 patients were cured with linezolid.






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