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Anthony L. Estrera
Taek-Yeon Lee
Riad Meada
Adel Irani
Hazim J. Safi
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Ann Thorac Surg 2007;83:1603-1609
© 2007 The Society of Thoracic Surgeons


Original Articles: Cardiovascular

Proximal Reoperations After Repaired Acute Type A Aortic Dissection

Anthony L. Estrera, MD*, Charles C. Miller, III, PhD, Martin A. Villa, MD, Taek-Yeon Lee, MD, PhD, Riad Meada, MD, Adel Irani, MD, Ali Azizzadeh, MD, Sheila Coogan, MD, Hazim J. Safi, MD

Department of Cardiothoracic and Vascular Surgery, University of Texas-Houston Medical School, Memorial Hermann Heart and Vascular Institute, Houston, Texas

Accepted for publication January 15, 2007.

* Address correspondence to Dr Estrera, Department of Cardiothoracic and Vascular Surgery, University of Texas-Houston Medical School, 6410 Fannin St, Suite 450, Houston, TX 77030 (Email: anthony.l.estrera{at}uth.tmc.edu).

Presented at the Fifty-third Annual Meeting of the Southern Thoracic Surgical Association, Tucson, AZ, Nov 8–11, 2006.

Background: Concerned with the associated risks of proximal reoperation, some have proposed an aggressive approach of aortic root replacement during emergent repair of acute type A aortic dissection. Because few data exist regarding late reoperations, we report outcomes of proximal reoperation after repaired type A aortic dissection.

Methods: Between January 1991 and March 2006, 63 patients underwent reoperation after previous repair for acute type A aortic dissection. Procedures performed at reoperation included ascending (94%, 59 of 63), total arch (62%, 39 of 63), elephant trunk (56%, 35 of 63), aortic valve replacement (38%, 24 of 63), aortic root (27%, 17 of 63), and coronary artery bypass graft (8%, 5 of 63). Preoperative, operative, and postoperative variables were analyzed retrospectively with regard to early and late mortality.

Results: Thirty-day mortality was 11.1% (7 of 63). No strokes occurred. Incidence of renal failure, respiratory failure, and bleeding was 6% (4 of 63), 23% (15 of 63), and 6% (4 of 63), respectively. Mean time from initial repair to reoperation was 69 months (range, 1 to 258). Procedure performed (root versus ascending/resuspension) at initial repair did not affect the time to reoperation (p > 0.05). Median follow-up was 40 months; and 1-, 5-, and 10-year survival was 82%, 74%, and 62%, respectively. Multivariate predictors of late mortality were prior coronary artery bypass graft surgery (odds ratio = 6.5, p < 0.003), bypass time (odds ratio = 3.6, p < 0.02), and renal dysfunction (odds ratio = 3.7, p < 0.05).

Conclusions: Proximal reoperations for repaired acute type A aortic dissection can be performed with acceptable early and late mortality. The concern for proximal reoperation should not dictate the initial procedure choice during acute type A aortic dissection. Continued clinical and radiographic surveillance of repaired type A aortic dissection is warranted.




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