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Ann Thorac Surg 2007;83:314-315
© 2007 The Society of Thoracic Surgeons

Case Reports

Prolonged Survival Due to Spontaneous Regression and Surgical Excision of Malignant Mesothelioma

John E. Pilling, MRCSa, Andrew G. Nicholson, FRCPathb, Clive Harmer, FRCPc, Peter Goldstraw, FRCSa,*

a Department of Thoracic Surgery, London, United Kingdom
b Department of Pathology, Royal Brompton Hospital, London, United Kingdom
c Department of Oncology, Royal Marsden Hospital, London, United Kingdom

Accepted for publication May 15, 2006.

* Address correspondence to Prof Goldstraw, Department of Thoracic Surgery, Royal Brompton Hospital, Sydney St, London, SW36NP United Kingdom (Email: p.goldstraw{at}rbh.nthames.nhs.uk).

We report a case of malignant pleural mesothelioma with histologically proven spontaneous regression of pleural disease. During a 12-year follow-up there was a single recurrence, which was a lesion in the chest wall at 6 years that was surgically excised. A prominent host response to tumor was seen in both the primary tumor and the recurrence.






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