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Michael Lanuti
Cameron D. Wright
Henning A. Gaissert
John C. Wain
Dean M. Donahue
Douglas J. Mathisen
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Ann Thorac Surg 2006;82:2037-2041
© 2006 The Society of Thoracic Surgeons


Original Articles: General Thoracic

Feasibility and Outcomes of an Early Extubation Policy After Esophagectomy

Michael Lanuti, MD*, Pierre E. de Delva, MD, Abdulrahman Maher, MD, Cameron D. Wright, MD, Henning A. Gaissert, MD, John C. Wain, MD, Dean M. Donahue, MD, Douglas J. Mathisen, MD

Division of General Thoracic Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts

Accepted for publication July 13, 2006.

* Address correspondence to Dr Lanuti, 55 Fruit Street, Blake 1570, Boston, MA 02114 (Email: mlanuti{at}partners.org).

Presented at the Poster Session of the Forty-second Annual Meeting of The Society of Thoracic Surgeons, Chicago, IL, Jan 30–Feb 1, 2006.

BACKGROUND: Although early extubation of esophagectomy patients has been found to be feasible, safe, and associated with low morbidity, there is no uniform standard of care among high volume centers. Our objective is to examine a contemporary series of esophagectomies and identify the feasibility and outcome of an early extubation policy.

METHODS: This study is a retrospective review of all patients who underwent esophagectomy between January 2003 and December 2004 at the Massachusetts General Hospital. One hundred and two patients were analyzed from 129 consecutive patients who underwent esophagectomy and subsequently divided in two groups: The early extubation group was extubated in the operating room and the late extubation group was extubated in the intensive care unit (ICU).

RESULTS: Ninety percent were extubated early. Although most patients underwent a transthoracic or thoracoabdominal esophagectomy, the operative approach did not influence failure to extubate. Neoadjuvant therapy was not predictive of extubation failure. Most patients age 70 or greater (86%) were extubated early. There were three nonelective reintubations in the early extubation group secondary to acute respiratory distress syndrome. The median length of stay was 11 days and median ICU stay was one day. The 30-day mortality was 1.9% and the median survival was 28 months.

CONCLUSIONS: Attention to restricted intraoperative fluid balance, limited blood loss, anesthetic technique, and epidural use permit most patients undergoing esophageal resection to be safely extubated immediately postresection in the operating room.







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