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Manoj Kuduvalli
Sanjay V. Ghotkar
Antony D. Grayson
Brian M. Fabri
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Ann Thorac Surg 2006;82:1356-1361
© 2006 The Society of Thoracic Surgeons

Original Articles: Cardiovascular

Edge-to-Edge Technique for Mitral Valve Repair: Medium-Term Results With Echocardiographic Follow-Up

Manoj Kuduvalli, FRCS (CTh)a,*, Sanjay V. Ghotkar, FRCSa, Antony D. Grayson, BSb, Brian M. Fabri, FRCS(Ed)a

a Department of Cardiothoracic Surgery, Cardiothoracic Centre Liverpool, Liverpool, United Kingdom
b Department of Research and Development, Cardiothoracic Centre Liverpool, Liverpool, United Kingdom

Accepted for publication May 4, 2006.

* Address correspondence to Dr Kuduvalli, Cardiothoracic Surgery, Cardiothoracic Centre NHS Trust, Thomas Dr, Liverpool L14 3PE, United Kingdom (Email: manojkud{at}hotmail.com).

BACKGROUND: The follow-up data for the Alfieri edge-to-edge technique of mitral valve repair is still a matter of interest. We describe the medium-term results of a single surgeon's practice with clinical and echocardiographic follow-up.

METHODS: Between October 1998 and July 2003, 41 patients underwent the Alfieri repair. Mean age of the patients was 68 years, 34.2% were female, 26 (63.41%) had New York Heart Association (NHYA) class III symptoms, and 19 (46.3%) had concomitant coronary disease. Preoperatively, 26 patients had grade 4+, 12 patients had grade 3+, and 3 patients had grade 2+ mitral regurgitation. The pathologies included myxomatous degeneration (73.2%), ischemic cardiomyopathy (12.2%), rheumatic (4.9%), dilated cardiomyopathy (2.4%), previous infection (2.4%), and indeterminate pathology (4.9%). Thirty-three patients (80.4%) had a ring annuloplasty, and 17 (41.4%) had concomitant coronary surgery. Median duration of echocardiographic follow-up was 22.1 months (range, 0.2 to 60.1).

RESULTS: Hospital mortality was 4.8% (2 of 41). Four patients underwent reintervention on the mitral valve. At follow-up, 26 patients (66.6%) were in NYHA class I. The actuarial freedom from death or reoperation at 5 years was 80.4%. Transthoracic echocardiography was performed in 94.3% of the 35 hospital survivors who did not undergo reoperation. Twenty-nine patients (87.8%) had grade 0–1+ mitral regurgitation, and the remainder had grade 2+ mitral regurgitation. All patients discharged from hospital were alive in December 2005.

CONCLUSIONS: The Alfieri edge-to-edge repair for mitral regurgitation is a safe and useful technique and should be included in the armamentarium of the mitral valve surgeon.




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 Ann. Thorac. Surg.Home page
L. Aklog and B. J. deGuzman
Edge-to-Edge Mitral Valve Repair: A "Safe and Useful" Technique?
Ann. Thorac. Surg., June 1, 2007; 83(6): 2261 - 2262.
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