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Ann Thorac Surg 2006;82:812-818
© 2006 The Society of Thoracic Surgeons

Original article: Cardiovascular

Cognitive Function in Candidates for Coronary Artery Bypass Graft Surgery

Christine S. Ernest, DPsycha,*, Barbara M. Murphy, PhDa, Marian U.C. Worcester, PhDa, Rosemary O. Higgins, GradDip BehHltha, Peter C. Elliott, PhDa, Alan J. Goble, MD, FRACPa, Michael R. Le Grande, MPHa, Natalie Genardini, DPsycha, James Tatoulis, MS, FRACSb

a Heart Research Centre, Melbourne, Australia
b Department of Cardiothoracic Surgery, The Royal Melbourne Hospital, Melbourne, Australia

Accepted for publication April 3, 2006.

* Address correspondence to Dr Ernest, Heart Research Centre, Box 2137 Post Office, The Royal Melbourne Hospital, Victoria 3050, Australia (Email: christine.ernest{at}heartresearchcentre.org).

BACKGROUND: While many studies have investigated cognitive impairments in patients after coronary artery bypass graft surgery, very few have closely evaluated presurgical cognitive functioning of bypass candidates.

METHODS: A battery of neuropsychologic tests was administered to a consecutive series of patients listed for bypass surgery (n = 109). Cognitive function of bypass candidates was compared with that of a healthy control group (n = 25) and published test norms.

RESULTS: Cognitive test scores in candidates for bypass were significantly lower than those of the control group on tests of attention, information processing speed, and verbal memory. Additionally, bypass candidates' cognitive test scores were significantly reduced compared with expected values derived from validated test norms, on all but one cognitive test.

CONCLUSIONS: Cognitive performances of candidates for bypass were significantly lower than those of a healthy control group and published cognitive test norms.




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