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Ann Thorac Surg 2006;82:158-163
© 2006 The Society of Thoracic Surgeons

Original article: Cardiovascular

Repair of Coarctation of the Aorta in Infants Weighing Less Than 2 Kilograms

Catherine D. Sudarshan, MD, FRCS, Andrew D. Cochrane, FRACS, FRCS (CTh) * , Zhang H. Jun, MD, Rodrigo Soto, MD, Christian P. Brizard, MD

Cardiac Surgery Unit, Royal Children's Hospital, Parkville, Victoria, Australia

Accepted for publication March 3, 2006.

* Address correspondence to Dr Cochrane, Cardiac Surgery Unit, Royal Children's Hospital, Flemington Rd, Parkville, Victoria 3052, Australia (Email: andrew.cochrane{at}rch.org.au).

BACKGROUND: We retrospectively reviewed our experience in aortic coarctation repair on infants weighing less than 2 kg to evaluate the results and assess the rate of recoarctation in this group of patients.

METHODS: Twenty-four consecutive babies weighing 2 kg or less were operated on over a period of 15 years. Median gestational age was 33 weeks (range, 30 to 36), and median weight was 1.6 kg (range, 1.0 to 2.0). Seventeen of them had associated cardiac anomalies. The methods of repair undertaken were resection with extended end-to-end anastomosis (n = 13), subclavian flap angioplasty (n = 9), carotid flap angioplasty (n = 1), and patch repair using pulmonary homograft tissue (n = 1).

RESULTS: Mean follow-up was 52.5 months (range, 0.5 to 151). There were 3 in-hospital deaths and 2 late deaths. Recoarctation developed in 7 babies. Four underwent balloon dilatation; 1 of them required further surgery; 3 others have mild recoarctation, but have not required further intervention. Risk factor analyses revealed that the presence of preoperative congestive cardiac failure, and coexisting noncardiac lesions as well as the duration of descending aortic cross-clamp and postoperative ventilation had a significant influence on mortality after repair.

CONCLUSIONS: Coarctation repair in infants less than 2 kg can be performed safely. The incidence of recoarctation is acceptable and comparable with that of other pediatric cohorts that have been reported. Preoperative cardiac function and associated noncardiac lesions may influence the incidence of mortality after repair. Delaying the timing of surgical repair to achieve growth is not necessary.




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P. T. Burch, C. G. Cowley, R. Holubkov, D. Null, L. M. Lambert, P. C. Kouretas, and J. A. Hawkins
Coarctation repair in neonates and young infants: Is small size or low weight still a risk factor?
J. Thorac. Cardiovasc. Surg., September 1, 2009; 138(3): 547 - 552.
[Abstract] [Full Text] [PDF]


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