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Katsuya Watanabe
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Ann Thorac Surg 2006;81:1904-1906
© 2006 The Society of Thoracic Surgeons

Case report

Anterior Mediastinal Mass in a Patient With Graves' Disease

Kazuki Yamanaka, MD a , * , Haruhiko Nakayama, MD a , Katsuya Watanabe, MD a , Yoichi Kameda, MD b

a Division of Thoracic Surgery, Kanagawa Cancer Center, Yokohama, Japan
b Division of Pathology, Kanagawa Cancer Center, Yokohama, Japan

Accepted for publication July 26, 2005.

* Address correspondence to Dr Yamanaka, Department of Thoracic Surgery, Yokohama Rosai Hospital, 3211, Kozukue-cho, Kohoku-ku, Yokohama, 222-0036 Japan (Email: kaz-genesis{at}mvb.biglobe.ne.jp).

Thymic hyperplasia is a common feature in Graves' disease. However, in most cases, thymic enlargement is minimal, and radiologically detectable massive enlargement of the thymus is infrequently reported. Half of them undergo thymectomy due to the concern about a thymoma. We report a 28-year-old woman with untreated Graves' disease. She had an anterior mediastinal mass that was diagnosed as true thymic hyperplasia by biopsy and disappeared after treatment of the hyperthyroid state. Recognizing the association between thymic hyperplasia and Graves'disease, and existence of the benign course after treatment of the hyperthyroidism may be useful for avoiding unnecessary surgical procedure.




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R. A. Kubicky, E. N. Faerber, J.-P. de Chadarevian, S. Wu, I. Rezvani, and F. De Luca
An Adolescent With a Mediastinal Mass, Diagnosed With Graves Disease and Thymic Hyperplasia
Pediatrics, February 1, 2010; 125(2): e433 - e437.
[Abstract] [Full Text] [PDF]


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