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Ann Thorac Surg 2006;81:1877-1879
© 2006 The Society of Thoracic Surgeons

Case report

Cartilaginous and Osseous Metaplasia With Bone Marrow Formation in the Aortic Valve of a Patient With Giant Cell Aortitis

Nicholas A. Charokopos, MD, PhD a , * , Polichronis Antonitsis, MD a , Efthymia Rouska, MD a , Ioannis Kostopoulos, MD, PhD b , Adnan Charaf, MD a , Panagiotis K. Spanos, MD, PhD a

a Department of Thoracic and Cardiovascular Surgery, AHEPA University Hospital, Aristotelian University of Thessaloniki, Thessaloniki, Greece
b Department of Pathology Medical School, Aristotelian University of Thessaloniki, Thessaloniki, Greece

Accepted for publication July 13, 2005.

* Address correspondence to Dr Charokopos, 22 Grigoriou E' St, Panorama, Thessaloniki, 55 236 Greece (Email: charokoposnick{at}hotmail.com).

We describe the case of a 40-year-old man who presented with an ascending aortic aneurysm and aortic valve regurgitation. The patient underwent a Bentall surgical procedure. Pathologic findings were consistent with giant cell aortitis with synchronous cartilaginous and osseous metaplasia with bone marrow formation in the degenerated aortic valve. The coexistence of these findings has not been previously reported in the English language literature.






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