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You Sun Hong
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Ann Thorac Surg 2006;81:1317-1324
© 2006 The Society of Thoracic Surgeons


Original article: Cardiovascular

Long-Term Clinical Results of Tricuspid Valve Replacement

Byung-Chul Chang, MD * , Sang-Hyun Lim, MD, Gijong Yi, MD, You Sun Hong, MD, Sak Lee, MD, Kyung-Jong Yoo, MD, Meyun Shick Kang, MD, Bum Koo Cho, MD

Department of Thoracic and Cardiovascular Surgery, Cardiovascular Center, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea

Accepted for publication November 3, 2005.

* Address correspondence to Dr Chang, Division of Cardiovascular Surgery, Yonsei Cardiovascular Center, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul, South Korea 120-752 (Email: bcchang{at}yumc.yonsei.ac.kr).

Presented at the Forty-first Annual Meeting of The Society of Thoracic Surgeons, Tampa, FL, Jan 24–26, 2005.

BACKGROUND: Tricuspid valve replacement (TVR) has been performed with mechanical or bioprosthetic valves. However, the relative advantages of the two types are incompletely known.

METHODS: Between 1978 and 2003, we performed 138 TVR (35 bioprosthetic, 103 mechanical) in 125 patients (50 men, 75 women), with a mean age of 43.7 ± 16.6 years. The diseases that required TVR were rheumatic (94), prosthetic valve failure (14), congenital (14), infective endocarditis(5), isolated tricuspid regurgitation (4), and miscellaneous conditions (7). The operations included the following: isolated TVR (41), double valve replacement (58), and triple valve replacement (39). The follow-up rate was 98.3%, and cumulative follow-up was 828.5 patient-years.

RESULTS: There were 22 in-hospital deaths (17.6%) and 13 (10.4%) late deaths. Fourteen patients required additional operations. There were 33 postoperative valve-related events including 11 thromboembolisms and 3 bleeding episodes. Kaplan-Meier survival for the entire group at 15 years was 73.8 ± 8.5% (bioprosthetic: 70.2 ± 10.4%, mechanical: 66.0 ± 19.4%). At 15 years, freedom from reoperation was 66.3 ± 9.4% (bioprosthetic: 55.1 ± 13.8%, mechanical: 86.0 ± 6.2%) and freedom from valve-related events was 49.9 ± 8.0%. The linearized incidence of valve thrombosis was 1.28%/patient-year (bioprosthetic: 0, mechanical: 1.92), anticoagulation-related bleeding was 0.37%/patient-year (mechanical: 0.54), reoperation was 1.71%/patient-year (bioprosthetic: 2.68, mechanical: 1.25), and valve-related events were 4.33%/patient-year (bioprosthetic: 3.83, mechanical: 4.6).

CONCLUSIONS: Both bioprosthetic and mechanical valves revealed similar long-term outcomes. However, findings suggest that greater care is needed to prevent valve thrombosis in mechanical valves in the early postoperative period, and there is a greater chance for reoperation in bioprosthetic valves.




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