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Ann Thorac Surg 2006;81:892-895
© 2006 The Society of Thoracic Surgeons

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Original article: Cardiovascular

Late Vascular Complications After Extracorporeal Membrane Oxygenation Support

^a Department of Cardiothoracic Surgery, Medical University Vienna, Vienna, Austria
^b Department of Vascular Surgery, Medical University Vienna, Vienna, Austria
^c Department of Clinical Pharmacology, Medical University Vienna, Vienna, Austria

Accepted for publication September 26, 2005.

^_* Address correspondence to Dr Zimpfer, Department of Cardiothoracic Surgery, Medical University Vienna, Wahringer Guertel 18-20, A-1090 Vienna, Austria (Email: daniel.zimpfer{at}meduniwien.ac.at).

BACKGROUND: Extracorporeal membrane oxygenation support through the groin vessels is an established treatment option for patients with life-threatening conditions, resistant to medical treatment. However, because of critical status and type of vascular access, late vascular complications are a potential risk.

METHODS: From January 1998 through December 2004, 174 adults (mean age, 45 ± 19 years) undergoing either cardiac surgery (n = 54, 31.4%) or lung transplantation (n = 120, 68.6%) were supported with extracorporeal membrane oxygenation. Data were prospectively collected and retrospectively analyzed. Follow-up extended up to 60 months (mean, 30 ± 10 months). Multivariable regression analysis was used to identify predictors of late vascular complications.

RESULTS: Hospital survival was 57.3%. A total of 12 hospital survivors (12.2%) experienced late vascular complications. All late vascular complications were local stenosis at the former arterial cannulation site. Treatment was done by means of femorofemoral crossover bypass (n = 3), iliofemoral bypass (n = 1), thromboendarterectomy (n = 3), and percutaneous transluminal angioplasty (n = 5). We experienced no limb loss during follow-up. Predictors for long-term vascular complications were technical problems during extracorporeal membrane oxygenation explantation (p = 0.002; odds ratio, 23.2) and history of peripheral vascular disease (p = 0.015; odds ratio, 3.1).

CONCLUSIONS: Extracorporal membrane oxygenation support is associated with the development of late vascular complications at the femoral access site. In selected patients alternative cannulation sites should be considered.

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