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Ann Thorac Surg 2006;81:880-885
© 2006 The Society of Thoracic Surgeons


Original article: Cardiovascular

Prolonged Intensive Care Unit Stay in Cardiac Surgery: Risk Factors and Long-Term-Survival

Ortrud Vargas Hein, MD a , * , Jürgen Birnbaum, MD a , Klaus Wernecke, MD b , Michael England, MD d , Wolfgang Konertz, MD c , Claudia Spies, MD a

a Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte, Charite-University Medicine Berlin, Berlin, Germany
b Department of Biometry, Campus Charité Mitte, Charite-University Medicine Berlin, Berlin, Germany
c Department of Cardiac Surgery, Campus Charité Mitte, Charite-University Medicine Berlin, Berlin, Germany
d Department of Anesthesia, New England Medical Center, Boston, Massachusetts

Accepted for publication September 30, 2005.

* Address correspondence to Dr Vargas Hein, Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte, Charité-University Medicine Berlin, Schumannstrasse 20/21, D-10117 Berlin, Germany (Email: ortrud.vargas{at}charite.de).

BACKGROUND: Risk factors have been found for prolonged intensive care unit (ICU) stay in cardiac surgery patients in only a few studies; conflicting results have been described. The focus of this study was twofold: first, to evaluate preoperative, intraoperative, and postoperative risk factors for ICU stay greater than 3 days in a cardiac surgery patient population; second, to evaluate long-term survival in cardiac surgery patients with prolonged ICU stay.

METHODS: Records from 2,683 cardiac surgery patients were retrospectively evaluated. Univariate and multivariate analyses for risk factors were performed for an ICU stay greater than 3 days. Thereafter, 2,563 patients were enrolled in a follow-up study for an observational time of 3 years after surgery.

RESULTS: Mortality was dependent on renal, respiratory, and heart failure, as well as age, elevated APACHE II scores, and reexploration. Long-term survival analyses demonstrated a significantly lower survival in patients with longer ICU stay. However, the 6-month to 3-year long-term survival was comparable with survival in patients without prolonged ICU stay.

CONCLUSIONS: Because of the increasing acuity of patients needing cardiac surgery, it is important to identify those at risk for a prolonged ICU course. It is therefore of paramount interest to implement measures throughout their entire hospital stay that would maximize organ function to improve survival and resource utilization.




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