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Right arrow Mechanical Circulatory Assistance

Ann Thorac Surg 2006;81:1107-1109
© 2006 The Society of Thoracic Surgeons

Case report

Triple Bridge-to-Transplant in a Case of Giant Cell Myocarditis Complicated by Human Leukocyte Antigen Sensitization and Heparin-Induced Thrombocytopenia Type II

Soren Schenk, MD, Latif Arusoglu, MD, Michiel Morshuis, MD, Kazutomo Minami, MD, PhD, Peter Sarnowski, RN, Reiner Koerfer, MD, PhD, Aly El-Banayosy, MD *

Cardiovascular Surgery, Heart Center North Rhine-Westphalia, Bad Oeynhausen, Germany

Accepted for publication December 28, 2004.

* Address correspondence to Dr El-Banayosy, Cardiovascular Surgery, Heart Center NRW, Georgstrasse 11, 32545 Bad Oeynhausen, Germany (Email: abanayosy{at}hdz-nrw.de).

Bridge-to-bridge experience has documented the feasibility of a switch from short-term to long-term mechanical circulatory support until heart transplant. We describe a case of irreversible cardiogenic shock due to giant cell myocarditis treated consecutively with extracorporal membrane oxygenation, bi-ventricular assist device, and total artificial heart. The postoperative course was complicated by human leukocyte antigen sensitization and heparin-induced thrombocytopenia type II. Our patient successfully underwent heart transplant after 10 months of support and was discharged in good condition. This case illustrates suitable device selection for myocarditis and represents two treatable immunological complications.




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T. E. Warkentin, A. Greinacher, and A. Koster
Heparin-induced thrombocytopenia in patients with ventricular assist devices: are new prevention strategies required?
Ann. Thorac. Surg., May 1, 2009; 87(5): 1633 - 1640.
[Abstract] [Full Text] [PDF]


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