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Ann Thorac Surg 2005;80:2395-2401
© 2005 The Society of Thoracic Surgeons

Review

Autofluorescence Bronchoscopy and Endobronchial Ultrasound: A Practical Review

David Feller-Kopman, MD a , William Lunn, MD b , Armin Ernst, MD a , *

a Interventional Pulmonology, Beth Israel Deaconess Medical Center, Boston, Massachusetts
b Baylor College of Medicine, Houston, Texas

Accepted for publication April 25, 2005.

* Address correspondence to Dr Ernst, Interventional Pulmonology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA02215; (Email: aernst{at}bidmc.harvard.edu).

Endobronchial ultrasound (EBUS) and autofluorescence bronchoscopy (AFB) are the two technologies to have the largest impact on diagnostic bronchoscopy in the last forty years. The AFB utilizes inherent tissue properties to identify preinvasive lesions of the central airways. The EBUS can accurately define airway invasion versus compression from tumors, guide transbronchial needle aspiration of hilar and mediastinal lymph nodes, and predict, based on ultrasound morphology, whether peripheral nodules are benign or malignant. It is also extremely useful for determining the proximal and distal extent of tumors in and around the airway, and aid in surgical planning. This article will review the principles and clinical applications of these two technologies.




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