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Kai Ihnken
James I. Fann
Thomas A. Burdon
Norman E. Shumway
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Right arrow Transplantation - heart

Ann Thorac Surg 2005;80:1909-1911
© 2005 The Society of Thoracic Surgeons

Case report

Chronic Mitral Valve Rejection Requiring Replacement in a Nine-Year-Old Allograft

Kai Ihnken, MD a , d , James I. Fann, MD a , d , * , Thomas A. Burdon, MD a , d , Frances L. Johnson, MD c , e , Jon C. Kosek, MD b , f , Norman E. Shumway, MD, PhD a , d

a Department of Cardiothoracic Surgery, Stanford University, Stanford
b Department of Pathology, Stanford University, Stanford
c Division of Cardiology, Stanford University, Stanford
d Section of Cardiothoracic Surgery, Veterans Affairs Palo Alto Health Care System, Palo Alto, California
e Section of Cardiology, Veterans Affairs Palo Alto Health Care System, Palo Alto, California
f Section of Pathology, Veterans Affairs Palo Alto Health Care System, Palo Alto, California

Accepted for publication June 4, 2004.

* Address correspondence to Dr Fann, Department of Cardiothoracic Surgery, Stanford University Medical Center, 300 Pasteur Dr, Stanford, CA94305 (Email: jfann{at}stanford.edu).

A 43-year-old woman underwent mitral valve replacement for severe mitral regurgitation nine years after orthotopic heart transplant. Histopathology showed chronic rejection of the mitral valve with lymphocytic infiltrates. The patient is well at one year follow-up. This report describes an identified case of chronic mitral valve rejection requiring valve replacement.






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