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Balakrishnan Mahesh
Gianni Angelini
Massimo Caputo
Xu Yu Jin
Alan Bryan
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Ann Thorac Surg 2005;80:1151-1158
© 2005 The Society of Thoracic Surgeons

Review

Prosthetic Valve Endocarditis

Balakrishnan Mahesh, MS, FRCS a , c , * , Gianni Angelini, FRCS a , Massimo Caputo, MD a , Xu Yu Jin, PhD b , Alan Bryan, FRCS a

a Cardiothoracic Center, Bristol Royal Infirmary, Bristol
b Cardiothoracic Center, John Radcliffe Hospital, Oxford
c Heart Science Center, Harefield Hospital, Middlesex, United Kingdom

* Address reprint requests to Dr Mahesh, Transplant Immunology, Heart Science Center, Harefield Hospital, MiddlesexUB96JH, UK (Email: b.mahesh{at}imperial.ac.uk).

Prosthetic valve endocarditis is a catastrophic complication of cardiac valve replacement, associated with high mortality rates. Medical treatment is effective in a few instances of endocarditis involving the leaflets alone in bioprostheses. However, accurate diagnosis, better myocardial protection, and improved surgical strategies have led to better survival in patients undergoing surgery after failed conservative therapy. This comprehensive review addresses various issues involved in the management of this complication.




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