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Shu S. Lin
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Ann Thorac Surg 2005;80:717-719
© 2005 The Society of Thoracic Surgeons

Case report

Left Ventricular Assist Device as Destination Therapy in Doxorubicin-Induced Cardiomyopathy

Sinan A. Simsir, MD a , Shu S. Lin, MD, PhD a , Laura J. Blue, RN a , John P. Gockerman, MD b , Stuart D. Russell, MD b , Carmelo A. Milano, MD a , *

a Department of Surgery, Duke University Medical Center, Durham, North Carolina
b Department of Medicine, Duke University Medical Center, Durham, North Carolina

Accepted for publication February 10, 2004.

* Address reprint requests to Dr Milano, Department of Surgery, Box 3043, Duke Medical Center South, Durham, NC27710 (Email: milan002{at}mc.duke.edu).

Doxorubicin-induced cardiomyopathy is not uncommon and may progress to end-stage heart failure. Treatment of this condition with heart transplantation, however, requires that the primary malignancy be deemed "cured." We present the case of a 55- year-old woman who had doxorubicin-induced cardiomyopathy and non-Hodgkin’s lymphoma. The active status of her lymphoma precluded heart transplantation. She had end-stage heart failure and underwent the insertion of a left ventricular assist device as a destination therapy.






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